ABx Support™ is a carefully researched blend of the non- pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve, probiotic microorganisms documented to support the normal gastrointestinal microbiota during antibiotic therapy.†
S. boulardii has broad, versatile gastrointestinal effects. It stimulates intestinal brush border enzymes to maintain normal digestive functions.† It stimulates D-glucose and sodium absorption and produces short-chain fatty acids such as butyrate and acetate that nourish colon mucosa. L. rhamnosus is a transient Lactobacillus that colonizes the small intestines when regularly consumed.† It favorably enhances innate and acquired immunity. It decreases T cell proliferation, induces helper (CD4+) T cell hyporesponsiveness, increases phagocytic activity in peripheral white blood cells and killing activity in natural killer cells, and supports inflammation metabolism.†
L. rhamnosus significantly augments serum and mucosal secreted antibody responses. B. bifidum and B. breve are two species indigenous to the colon's microbiota. Bifidobacteria are highly beneficial for normal bowel function and are exquisitely sensitive to most antibiotics. Consumption of B. bifidum and B. breve replenishes colonic bifidobacterial populations suppressing overgrowth by undesirable microorganisms.† B. bifidum is among the many Bifidobacterium species normally found in large numbers in a healthy colon microbiota. B. bifidum activates B cells making them more responsive to transforming growth factor-1 and interleukin-5 for IgA secretion. B. bifidum enhances IgA response to immune challenge. Supplementation with B. bifidum supports white cell phagocytic activity.† B. breve increases the immune response of Peyer's patch cells stimulating B cell proliferation and antibody production.† Clinical studies of the probiotic species in ABx Support™ have shown these microorganisms support healthy intestinal function during antibiotic use.†
This hypoallergenic formulation is provided in vegetarian capsules in bottles of 28 capsules, a convenient 14-day supply for concurrent use during antibiotic therapy, or larger bottles of 60 capsules.